For Patients - United States

What is Severe Aortic Stenosis?

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Severe Aortic Stenosis

Severe aortic stenosis (AS) occurs when the aortic valve doesn’t open properly. This forces your heart to work harder to pump blood throughout your body. Over time, the heart muscle weakens. This affects your overall health and keeps you from participating in normal daily activities. Left untreated, severe AS is a very serious, life-threatening condition, leading to heart failure and increased risk for sudden cardiac death. Severe AS is often not preventable, causes narrowing of the aortic valve, and may be related to the following:

  • Age
  • A buildup of mineral (calcium) deposits that narrows the aortic valve (stenosis)
  • Radiation therapy
  • A history of a bacterial infection of the heart (rheumatic fever)
  • Increased fat in the blood vessels (high cholesterol)

Severe Aortic Stenosis Image

 

Symptoms of Severe AS

Signs and symptoms of severe AS can include:

  • Chest pain or tightness
  • Feeling faint or fainting with activity
  • Dizziness
  • Fatigue
  • Shortness of breath
  • Irregular heart beat (palpitations)
  • Unusual sound heard during a heartbeat (murmur)
 

Is CoreValve Transcatheter Aortic Valve Replacement (TAVR) Right for You?

CoreValve TAVR may be right for you if you feel sick from severe aortic stenosis and your doctor has determined that you are not a candidate for open heart valve replacement surgery. Your doctor can help decide if CoreValve TAVR is the appropriate treatment option for you.